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The preparation of a brain targeted artificial nano-enzyme and application
Reference #: 01514
The University of South Carolina is offering licensing opportunities for The preparation of a brain targeted artificial nano-enzyme and application
Background:
Chronic neuroinflammation is caused by the activation of microglia, which is the major cause of central neuronal system (CNS) diseases, including Alzheimer’s disease,...
Published: 8/17/2026
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Updated: 6/9/2022
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Inventor(s): Peisheng Xu, Haijun Liu
Keywords(s): Alzheimer’s disease, Amyotrophic lateral sclerosis, brain injury, Brain targeted nanoparticle, Brain tumor, Epilepsy, frontotemporal dementia, glioblastoma, Huntington's disease, Multiple sclerosis, neonatal hypoxic-ischemic, neuroblastoma, Parkinson's disease, post-traumatic stress disorder, Spinal cord injury, stroke
Category(s): Nanotechnology, Health Sciences, Biomedical and Life Sciences
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Nanoparticle for the remodeling of cancer-associated fibroblast
Reference #: 01513
The University of South Carolina is offering licensing opportunities for Nanoparticle for the remodeling of cancer-associated fibroblast
Background:
The biomimetic enzyme activity of the cerium oxide nanoparticle (CeNP) prefers ultrasmall particle size and bare surface. Unfortunately, those two features are not favorable for its...
Published: 1/21/2026
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Updated: 6/9/2022
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Inventor(s): Peisheng Xu
Keywords(s): cancer, cancer metastasis, cancer treatment, cancer-associated fibroblast, tumor microenvironment remodeling
Category(s): Nanotechnology, Health Sciences, Biomedical and Life Sciences
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Carrier-Free Curcumin Nanoparticle for EGFR Positive Cancer Therapy
Reference #: 01472
The University of South Carolina is offering licensing opportunities for Carrier-free curcumin nanoparticle for EGFR positive cancer therapy
Background:
Due to their small size and large surface area, drug nanoparticles show great promise in improving drug delivery in patients.
Invention Description:
Most nanoparticle based...
Published: 10/8/2025
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Updated: 3/12/2021
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Inventor(s): Peisheng Xu
Keywords(s): cancer, carrier-free, curcumin, EGFR receptor, erlotinib, nanoparticle, Nanotechnology
Category(s): Health Sciences, Biomedical and Life Sciences, Nanotechnology
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The Preparation of Dual-Targeted Nano-Cocktail and its Application in Cancer Therapy
Reference #: 01404
The University of South Carolina is offering licensing opportunities for Preparation of Dual-Targeted Nano-Cocktail and its Application in Cancer Therapy
Background:
Due to the heterogeneous nature of tumors and the limitation of anticancer drugs, a mono-compound treatment usually can only kill a fraction of cancer cells while...
Published: 9/4/2022
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Updated: 10/24/2019
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Inventor(s): Peisheng Xu, Binglin Sui
Keywords(s): cancer treatment, drug delivery, dual responsive, hetero-targeted, Nano-cocktail
Category(s): Chemistry and Biochemistry, Nanotechnology, Biomedical and Life Sciences, Health Sciences
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Fabrication of Suramin-loaded Nanoparticle and its Application
Reference #: 01386The University of South Carolina is offering licensing opportunities for the fabrication of suramin loaded nanoparticle and its application.Background:Most anti-cancer drugs damage normal cells as they kill cancer cells, causing patients to suffer from side effects like heart tissue and kidney damage. It has been shown that suramin...
Published: 9/4/2022
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Updated: 3/15/2019
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Inventor(s): Peisheng Xu
Keywords(s): anti-angiogenesis, anti-metastasis, enhanced anticancer efficacy, heart and kidney protection, Minimizing side effects, overcome multi-drug resistance
Category(s): Chemistry and Biochemistry, Nanotechnology, Biomedical and Life Sciences, Health Sciences
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Cell Membrane Coated Nanoparticle for Brain Targeted Drug Delivery
Reference #: 01315The University of South Carolina is offering licensing opportunities for a Cell Membrane Coated Nanoparticle for Brain Targeted Drug Delivery.Background:Due to the existence of blood brain barrier (BBB), most of the small molecules for the treatment of central neural systems (CNS) diseases cannot cross the BBB. Development of efficient...
Published: 6/5/2026
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Updated: 3/30/2018
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Inventor(s): Peisheng Xu
Keywords(s):
Category(s): Biomedical and Life Sciences, Chemistry and Biochemistry, Health Sciences, Nanotechnology
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Polydopamine Coated PLGA Nanoparticle for Photothermal Therapy
Reference #: 01169 The University of South Carolina is offering licensing opportunities for a biodegradable, photothermal-responsive nanoparticle that can be used for disease therapy, drug delivery, and other biomedical applications.Invention Description: The subject invention is a dual-functional, photothermal nanoparticle that not only delivers therapeutic...
Published: 5/27/2021
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Updated: 11/19/2015
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Inventor(s): Peisheng Xu, Huacheng He
Keywords(s):
Category(s): Biomedical and Life Sciences, Nanotechnology, Health Sciences
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The Preparation of Brain Targeted Nanoparticle and its Application
Reference #: 01155The University of South Carolina is offering licensing opportunities for a nanocarrier that can effectively pass the blood-brain barrier and deliver therapeutic drugs to diseased tissue by taking advantage of the physiological characteristics of brain.Invention Description:The subject invention is a dual targeted and dual responsive...
Published: 8/17/2026
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Updated: 7/22/2015
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Inventor(s): Peisheng Xu, Eleni Markoutsa
Keywords(s):
Category(s): Biomedical and Life Sciences, Health Sciences, Nanotechnology
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The Preparation of Polymeric Prodrug of Disulfiram and its Application
Reference #: 01145The University of South Carolina is offering licensing opportunities for a polymeric prodrug that is able to kill a broad-spectrum of cancer cells, including drug resistant cancer cells and cancer stem cells, without damaging normal cells.Invention Description:The present invention describes the preparation of a polymeric prodrug of...
Published: 9/16/2025
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Updated: 1/20/2015
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Inventor(s): Peisheng Xu, Huacheng He
Keywords(s):
Category(s): Biomedical and Life Sciences, Health Sciences
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Polymer/Copper Combination for Cancer Targeted Therapy
Reference #: 01140
The University of South Carolina is offering licensing opportunities for a polymer/copper formulation to treat cancer.
Invention Description:
The subject invention is a polymer/copper combination drug that can selectively kill a wide-spectrum of cancer cells without affecting normal cells.
Potential Applications:
Cancer treatment
Advantages...
Published: 8/12/2026
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Updated: 11/24/2014
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Inventor(s): Peisheng Xu, Huacheng He
Keywords(s):
Category(s): Biomedical and Life Sciences, Health Sciences
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