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Cyclopropanol as a bioorthogonal warhead for electrochemically controlled bioconjugation applications

Reference #: 1685 The University of South Carolina is offering licensing opportunities for Cyclopropanol as a bioorthogonal warhead for electrochemically controlled bioconjugation applications. Background: Bioconjugation techniques play an important role in modern chemical biology and biomedical sciences, such as protein drug stabilization, target...

Published: 6/12/2024 | Inventor(s): Qian Wang, Shan Hu

Keywords(s):

Category(s): Biomedical and Life Sciences, Health Sciences

Novel treatment for pseudomyxoma peritonei

Reference #: 1692 The University of South Carolina is offering licensing opportunities for Novel treatment for pseudomyxoma peritonei. Background: Pseudomyxoma peritonei (PMP) is a rare cancer, which originates as an appendiceal neoplasm. Due to its usually poor vascularization and floating as nodules, PMP spreads easily to the peritoneal cavity,...

Published: 6/11/2024 | Inventor(s): Jie Li, Daping Fan, Hexin Chen, Traci Testerman

Keywords(s):

Category(s): Biomedical and Life Sciences, Health Sciences

Immunomodulating Activities of Alistipes and Its Metabolites: Mechanism and Application

Reference #: 1678 The University of South Carolina is offering licensing opportunities for Immunomodulating Activities of Alistipes and Its Metabolites: Mechanism and Application. Background: The gut microbiota plays a key role in health and disease. The balance between beneficial genera (such as Alistipes and Odoribacter) and harmful species (such...

Published: 6/11/2024 | Inventor(s): Jie Li, Hexin Chen, Daping Fan

Keywords(s):

Category(s): Biomedical and Life Sciences, Health Sciences

Drug repurposing for treatment of congenital vascular malformations

Reference #: 1659 The University of South Carolina is offering licensing opportunities for Drug Repurposing for Treatment of Congenital Vascular Malformations. Background: Congenital vascular malformations (CVM) are a major threat to public health with a 1.5% incident rate in the general population. Congenital capillary malformation (CM), a.k.a.,...

Published: 7/1/2024 | Inventor(s): Wenbin Tan, Vi Nguyen, Chao Gao, Anil Jegga, Yunguan Wang, Sudhir Ghandikota, Marcelo Hochman

Keywords(s):

Category(s): Biomedical and Life Sciences, Health Sciences

Trigonelline mitigates cardiomyopathy caused by SARS-CoV-2 Spike protein under obesity

Reference #: 01642 The University of South Carolina is offering licensing opportunities for Trigonelline mitigates cardiomyopathy caused by SARS-CoV-2 spike protein under obesity. Background: Today, the spread of Coronavirus Disease 2019 (COVID-19) continues, and while millions of patients have recovered, a significant number experience prolonged...

Published: 5/17/2024 | Inventor(s): Wenbin Tan, Vi Nguyen, Taixing Cui

Keywords(s):

Category(s): Health Sciences, Biomedical and Life Sciences

Using EEG to predict delirium using limited lead device

Reference #: 01627 The University of South Carolina is offering licensing opportunities for Using EEG to predict delirium using limited lead device. Background: This study demonstrates a machine learning-based approach to detect delirium using limited lead EEG data with a high accuracy of 98% prior to the onset of clinical symptoms. In contrast to...

Published: 7/2/2024 | Inventor(s): Malissa Mulkey, Sunghan Kim, Baijain Yang

Keywords(s):

Category(s): Health Sciences, Biomedical and Life Sciences

Misty Plasma Dielectric Barrier Discharge Plasma System for Disinfection

Reference #: 01600 The University of South Carolina is offering licensing opportunities for Misty Plasma Dielectric Barrier Discharge Plasma System for Disinfection Background: Approximately 1.7 million healthcare-associated infections occur each year in the U.S., killing 98,000 patients. COVID-19 has revealed further weaknesses in the preparedness...

Published: 4/2/2024 | Inventor(s): Malik Tahiyat, Tanvir Farouk, Shamia Hoque, Traci Testerman

Keywords(s): cold atmospheric plasma, dielectric barrier discharge, disinfection, sterilization, water vapor plasma

Category(s): Biomedical and Life Sciences, Health Sciences

The value of microRNA-155 in breast cancer prognosis and treatment

Reference #: 01608 The University of South Carolina is offering licensing opportunities for The value of microRNA-155 in breast cancer prognosis and treatment Background: In the US in 2021, there were an estimated 281,550 new cases of invasive breast cancer diagnosed in women; 2,650 cases diagnosed in men. An estimated 44,130 breast cancer deaths...

Published: 4/2/2024 | Inventor(s): Daping Fan, Junfeng Wang,

Keywords(s): breast cancer, immune therapy, microRNA, microRNA-155, predictive biomarker, prognosis

Category(s): Health Sciences, Biomedical and Life Sciences

Click Chemistry Amplified Nanopore Assay for Ultrasensitive Quantification of Proteins

Reference #: 01610 The University of South Carolina is offering licensing opportunities for Click Chemistry Amplified Nanopore Assay for Ultrasensitive Quantification of Proteins Background: Despite major advances in HIV testing, ultrasensitive detection of early infection remains a key challenge, especially for the viral capsid protein p24, which...

Published: 2/2/2024 | Inventor(s): Chang Liu

Keywords(s): antibody, antigen, assay, biosensor, detection, diagnostic, HIV, nanopore, protein, quantification

Category(s): Biomedical and Life Sciences, Health Sciences

Abbapolins as Inhibitors and Degraders of Polo-Like Kinases

Reference #: 01593 The University of South Carolina is offering licensing opportunities for Abbapolins as Inhibitors and Degraders of Polo-Like Kinases Background: There are no effective treatments for castration-resistant prostate cancers as all current therapies eventually fail. Invention Description: Novel chemicals called abbapolins are described...

Published: 4/2/2024 | Inventor(s): Campbell Mcinnes, Michael Wyatt, Danda Chapagai, Jessy Stafford, Gursanker Ramamoorthy

Keywords(s): abbapolin, drug discovery, peptide, Polo Like Kinase

Category(s): Biomedical and Life Sciences, Health Sciences

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