Search Results - Biomedical+and+Life+Sciences

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Nepenthes GDSL Lipase to Treat Gut Lipid Malabsorption and Atrophy

Reference #: 1718 The University of South Carolina is offering licensing opportunities for Nepenthes GDSL Lipase to Treat Gut Lipid Malabsorption and Atrophy. Background: The absorption of dietary lipids in the small intestine is a fundamental biological process central to maintaining energy balances in tissues. Atrophy occurs when the energetic...

Published: 9/18/2024 | Inventor(s): Jason Kubinak

Keywords(s):

Category(s): Health Sciences, Biomedical and Life Sciences

Neural repair through inhibition of Reg3A signaling

Reference #: 1677 The University of South Carolina is offering licensing opportunities for Neural repair through inhibition of Reg3A signaling. Background: Human peripheral nerve regeneration is rarely successful when the nerve's axons must regrow more than 5-6 cm. By the time the regenerating axons in the nerve get past 5-6 cm, the environment...

Published: 9/18/2024 | Inventor(s): Jeffery Twiss, Courtney Buchanan, Jinyoung Lee, Lauren Vaughn, Ashley Kalinski

Keywords(s):

Category(s): Biomedical and Life Sciences, Health Sciences

Engineering Immune Responses with Programmable Transcription Factors

Reference #: 1699 The University of South Carolina is offering licensing opportunities for Engineering Immune Responses with Programmable Transcription Factors. Background: The regulation immune activation pathways are the bedrock of immunotherapy treatments for cancer and infectious diseases. Strategies for activation typically include administering...

Published: 9/18/2024 | Inventor(s): Nicholas Truex, Lydia Pless, Hannah Ponder, Olivia Sherron, Ashley King, Victoria Beato

Keywords(s):

Category(s): Biomedical and Life Sciences, Health Sciences

Novel imidazothiazoles inhibiting indoleamine 2,3-dioxygenase 1 (IDO1) and tryptophan 2,3-dioxygenase (TDO)

Reference #: 1706 The University of South Carolina is offering licensing opportunities for Novel imidazothiazoles inhibiting indoleamine 2,3-dioxygenase 1 (IDO1) and tryptophan 2,3-dioxygenase (TDO). Background: The kynurenine pathway (KP) is involved in the modulation of many biological and physiological processes including immune response and neurotransmission....

Published: 10/7/2024 | Inventor(s): Yangmei Li

Keywords(s):

Category(s): Biomedical and Life Sciences, Health Sciences

A CCL8-based cytotoxic analog for cancer management

Reference #: 1721 The University of South Carolina is offering licensing opportunities for A CCL8-based cytotoxic analog for cancer management. Background: Deregulation of cytokine and chemokine networks is common in various malignancies and other pathologies and has causative role in disease progression. Despite however their acknowledged role in...

Published: 9/26/2024 | Inventor(s): Hippokratis Kiaris, Bernardo Chavez

Keywords(s):

Category(s): Health Sciences, Biomedical and Life Sciences

An amino acid hybrid of aCGRP to treat cardiovascular disease

Reference #: 01645 The University of South Carolina is offering licensing opportunities for An Amino Acid Hybrid of a CGRP to Treat Cardiovascular Disease. Background: Heart failure is a chronic condition affecting millions of people worldwide, often leading to reduced lifespan and poor quality of life. The American Heart Association (AHA) estimates...

Published: 8/29/2024 | Inventor(s): Jay Potts, Ambrish Kumar, Donald Dipette

Keywords(s):

Category(s): Biomedical and Life Sciences, Health Sciences

Cyclopropanol as a bioorthogonal warhead for electrochemically controlled bioconjugation applications

Reference #: 1685 The University of South Carolina is offering licensing opportunities for Cyclopropanol as a bioorthogonal warhead for electrochemically controlled bioconjugation applications. Background: Bioconjugation techniques play an important role in modern chemical biology and biomedical sciences, such as protein drug stabilization, target...

Published: 6/12/2024 | Inventor(s): Qian Wang, Shan Hu

Keywords(s):

Category(s): Biomedical and Life Sciences, Health Sciences

Novel treatment for pseudomyxoma peritonei

Reference #: 1692 The University of South Carolina is offering licensing opportunities for Novel treatment for pseudomyxoma peritonei. Background: Pseudomyxoma peritonei (PMP) is a rare cancer, which originates as an appendiceal neoplasm. Due to its usually poor vascularization and floating as nodules, PMP spreads easily to the peritoneal cavity,...

Published: 6/11/2024 | Inventor(s): Jie Li, Daping Fan, Hexin Chen, Traci Testerman

Keywords(s):

Category(s): Biomedical and Life Sciences, Health Sciences

Immunomodulating Activities of Alistipes and Its Metabolites: Mechanism and Application

Reference #: 1678 The University of South Carolina is offering licensing opportunities for Immunomodulating Activities of Alistipes and Its Metabolites: Mechanism and Application. Background: The gut microbiota plays a key role in health and disease. The balance between beneficial genera (such as Alistipes and Odoribacter) and harmful species (such...

Published: 8/13/2024 | Inventor(s): Jie Li, Hexin Chen, Daping Fan

Keywords(s):

Category(s): Biomedical and Life Sciences, Health Sciences

Nepenthes prolyl endopeptidases to suppress gluten sensitivity in humans

Reference #: 1673 The University of South Carolina is offering licensing opportunities for Nepenthes prolyl endopeptidases to suppress gluten sensitivity in humans. Background: It is currently estimated that 5% of the world's population suffers from gluten-related disorders, though this number is considered a gross underestimate due to the difficulties...

Published: 6/11/2024 | Inventor(s): Jason Kubinak

Keywords(s):

Category(s): Biomedical and Life Sciences

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